---
title: Technology overview | Camena Bioscience
description: Revolutionize DNA synthesis with gSynth®'s high-throughput solution for synthetic gene production. Next-level innovation of DNA synthesis technology.
---

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# gSynth®

#### The gSynth® platform is a proprietary synthesis engine developed to overcome the limitations of accuracy, speed, and scale.  It delivers high-fidelity constructs at the pace required for today’s high-velocity drug discovery.

 

 

![Camena Bio](https://www.camenabio.com/hs-fs/hubfs/Camena%20Bio%202024%20theme/Images/hero-shapes-big.png?width=2685&height=1860&name=hero-shapes-big.png)

## Engineered for performance

![Advanced automation](https://www.camenabio.com/hubfs/Vector%20(1).svg)

### Advanced lab automation

Streamlining the path from digital design to physical construct.  Rapid, consistent output of plates per week. 

![Precision design](https://www.camenabio.com/hs-fs/hubfs/scale.png?width=24&height=37&name=scale.png)

### Precision design

Proprietary design algorithm and enzymatic synthesis for sequence perfect results. 

![Manufacturing excellence](https://www.camenabio.com/hs-fs/hubfs/paper-icon.png?width=30&height=24&name=paper-icon.png)

### Manufacturing excellence

Reliability is the foundation of speed. ISO-certified quality management systems providing operational consistency.

![Consistent fidelity](https://www.camenabio.com/hs-fs/hubfs/sustainability.png?width=25&height=25&name=sustainability.png)

### Consistent fidelity

NGS verified and transfection-ready, for immediate downstream use.

 

![Camena Bioscience colleague working in the laboratory](https://www.camenabio.com/hs-fs/hubfs/tech-img-1.jpg?width=900&height=831&name=tech-img-1.jpg)

## A new era of DNA synthesis: next-level innovation

#### **The ability to read, write, and edit DNA is at the heart of the bioengineering biology value chain.**

Yet researchers are constrained by existing synthesis technologies, both chemical and enzymatic. Those technologies can be error-prone and have limited ability to produce the DNA sequences you need.

gSynth® has turned that on its head.

[Why we're TdT-free](https://www.camenabio.com/resources/heres-why-were-tdt-free) [Codon optimisation challenges](https://www.camenabio.com/resources/the-dark-side-of-codon-optimisation)

## How it works

#### **Precise *de novo* synthesis**

![Precise de novo synthesis](https://www.camenabio.com/hubfs/step1%20(1).webp "Precise de novo synthesis")

 Zoom +

A plate of generic gSynth reagents are pipetted into wells of a 384 well plate.  After pipetting each well contains a specific mixture of gSynth reagents.

#### **Addamers decapped and payloads extended**

![Step 2 no text update Mar 25 900](https://www.camenabio.com/hubfs/Step%202%20no%20text%20update%20Mar%2025%20900.jpg "Step 2 no text update Mar 25 900")

 Zoom +

A proprietary mix of enzymes de-caps Addamers and extends their payloads performing *de novo* synthesis of DNA sequences. 

#### **Algorithmic assembly of long DNA molecules**

![Step 3 text update Mar 25 900 (1)](https://www.camenabio.com/hs-fs/hubfs/Step%203%20text%20update%20Mar%2025%20900%20(1).png?width=900&height=900&name=Step%203%20text%20update%20Mar%2025%20900%20(1).png "Step 3 text update Mar 25 900 (1)")

 Zoom +

Addamers are combined to form longer DNA molecules.  Rapid synthesis producing multi-kb per day. 

- "Our partnership with Camena Bioscience has been outrageously successful."
  
  
  
  Strategic customer
  
  Top 20 Pharmaceutical company

![cb-img_8936](https://www.camenabio.com/hs-fs/hubfs/Camena%20Bio%202024%20theme/Images/cb-img_8936.jpg?width=3500&height=2000&name=cb-img_8936.jpg)

## The gSynth advantage

- Universal reagent starting set, compatible with common liquid handlers
- *De novo* synthesis of DNA produces any payload
- A combinatorial and parallel gene assembly approach that accurately and rapidly produces complex DNA sequences  
- Proprietary design algorithm based on geometric principles and bioinformatics software that can be integrated into existing workflows
- Produces readily clonable double-stranded DNA 
- Sequence and supply-chain security

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#### Our Technology

[gSynth® Platform](https://www.camenabio.com/technology)

 

 

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